ANTIBODIES AGAINST MICA AND/OR MICB AND USES THEREOF

ANTIBODIES AGAINST MICA AND/OR MICB AND USES THEREOF

The disclosure provides antibodies that specifically bind human MICA/B and methods of use thereof. In some aspects, the disclosure is directed to methods of treating a cancer in a subject, comprising administering to the subject an anti-MICA/B antibody.

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Bibliographische Detailangaben
Hauptverfasser: SRINIVASAN, Mohan, HUANG, Haichun, KORMAN, Alan J, BEZMAN, Natalie A, HUANG, Richard Y, STROP, Pavel, CHEN, Guodong, LEE, Peter Sung Keun, CAMDERE, Gamze Ozlem, KUHNE, Michelle Renee, GRAZIANO, Robert F, YIN, Yiming
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The disclosure provides antibodies that specifically bind human MICA/B and methods of use thereof. In some aspects, the disclosure is directed to methods of treating a cancer in a subject, comprising administering to the subject an anti-MICA/B antibody.