BISPECIFIC ANTI CLAUDIN XCD3 ANTIBODIES FOR TREATMENT OF CLAUDIN EXPRESSING CANCER DISEASES

BISPECIFIC ANTI CLAUDIN XCD3 ANTIBODIES FOR TREATMENT OF CLAUDIN EXPRESSING CANCER DISEASES

The present disclosure provides binding agents that contain a binding domain that is specific for CD3 allowing binding to T cells and a binding domain that is specific for a tumor-associated claudin molecule and methods of using these binding agents or nucleic acids encoding therefor for treating ca...

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Bibliographische Detailangaben
Hauptverfasser: STADLER, Christiane, FIEDLER, Markus, BÄHR-MAHMUD, Hayat, TÜRECI, Özlem, SAHIN, Ugur, HOLLAND, Julia, LE GALL, Fabrice, PLUM, Laura, BEISSERT, Tim, JENDRETZKI, Arne
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present disclosure provides binding agents that contain a binding domain that is specific for CD3 allowing binding to T cells and a binding domain that is specific for a tumor-associated claudin molecule and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.