COMPOSITIONS AND METHODS FOR INHIBITING INFLAMMATION

COMPOSITIONS AND METHODS FOR INHIBITING INFLAMMATION

As described below, the present invention features compositions and methods for inhibiting inflammation in connection with an acellular template (e.g., an electrospun template). In one embodiment, the template is impregnated with an agent (e.g., N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine ami...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FETZ, Allison E, RADIC, Marko Z, BOWLIN, Gary L
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:As described below, the present invention features compositions and methods for inhibiting inflammation in connection with an acellular template (e.g., an electrospun template). In one embodiment, the template is impregnated with an agent (e.g., N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide (Cl-amidine)) that inhibits a peptidylarginine deaminase (e.g., PAD4).