CHLOROQUINE GEL AND PREPARATION METHOD AND APPLICATION THEREFOR
The invention discloses a chloroquine gel and a preparation method and application thereof. The invention further provides a chloroquine nanosphere, which includes a water-soluble nanosphere carrier, and chloroquine or a chloroquine derivative, wherein a mass ratio of the chloroquine or the chloroqu...
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Format: | Patent |
Sprache: | eng ; fre ; ger |
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Zusammenfassung: | The invention discloses a chloroquine gel and a preparation method and application thereof. The invention further provides a chloroquine nanosphere, which includes a water-soluble nanosphere carrier, and chloroquine or a chloroquine derivative, wherein a mass ratio of the chloroquine or the chloroquine derivative to the water-soluble nanosphere carrier is no more than 1:3. According to the invention, the water-soluble nanosphere carrier and the chloroquine or the chloroquine derivative are jointly prepared into the nanosphere, which effectively solves problems of side effects and drug resistance of the chloroquine; can prolong a detention time of a medicine at a treated part, improve a bioavailability and a treatment effect of the medicine, can effectively treat an external genitalia infectious disease, and remarkably improve a curative effect; and not only expand an application range and an application scheme of the chloroquine, but is simple and convenient in preparation method, easy in synthesis without toxic and side effects, and has high safety; moreover, industrial application of a new medicine can be performed. |
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