FORMULATIONS COMPRISING CHELATORS, PERMEATION ENHANCERS AND HYDROXYETHYL CELLULOSE FOR TREATING OPHTHALMIC DISORDERS

An ophthalmic formulation, comprising a chelator (such as EDTA and its salts), and a transport enhancer (such as Methyl Sulfonyl Methane; MSM) and an effective amount of a viscoelastic polymer (such as hydroxymethyl cellulose; HEC) is provided. Together, the combination of the two substances unexpec...

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Hauptverfasser: BHUSHAN, Rajiv, GIN, Jerry, GOSWAMY, Amit
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creator BHUSHAN, Rajiv
GIN, Jerry
GOSWAMY, Amit
description An ophthalmic formulation, comprising a chelator (such as EDTA and its salts), and a transport enhancer (such as Methyl Sulfonyl Methane; MSM) and an effective amount of a viscoelastic polymer (such as hydroxymethyl cellulose; HEC) is provided. Together, the combination of the two substances unexpectedly and beneficially reduces discomfort associated with and increases efficacy of chelator/transport enhancer as compared to formulations without the viscoelastic polymer.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title FORMULATIONS COMPRISING CHELATORS, PERMEATION ENHANCERS AND HYDROXYETHYL CELLULOSE FOR TREATING OPHTHALMIC DISORDERS
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