FORMULATIONS COMPRISING CHELATORS, PERMEATION ENHANCERS AND HYDROXYETHYL CELLULOSE FOR TREATING OPHTHALMIC DISORDERS

An ophthalmic formulation, comprising a chelator (such as EDTA and its salts), and a transport enhancer (such as Methyl Sulfonyl Methane; MSM) and an effective amount of a viscoelastic polymer (such as hydroxymethyl cellulose; HEC) is provided. Together, the combination of the two substances unexpec...

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Bibliographische Detailangaben
Hauptverfasser: BHUSHAN, Rajiv, GIN, Jerry, GOSWAMY, Amit
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An ophthalmic formulation, comprising a chelator (such as EDTA and its salts), and a transport enhancer (such as Methyl Sulfonyl Methane; MSM) and an effective amount of a viscoelastic polymer (such as hydroxymethyl cellulose; HEC) is provided. Together, the combination of the two substances unexpectedly and beneficially reduces discomfort associated with and increases efficacy of chelator/transport enhancer as compared to formulations without the viscoelastic polymer.