SHEAR STRESS SENSITIVE LIPOSOMES

The invention relates to liposome vesicle comprising a membrane consisting of 1,3-diheptadecanamidopropan-2-yl (2-(trimethylammonio) ethyl) phosphate surrounding a volume comprising a pharmaceutical drug or contrast agent. The vesicle is mechanosensitive at body temperature and at physiologically or...

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Bibliographische Detailangaben
Hauptverfasser: PFOHL, Thomas, NEUHAUS, Frederik, GERGANOVA, Gabriela, MÜLLER, Dennis, MÜLLER, Bert, SAXER, Till, BUSCEMA, Marzia, MATVIYKIV, Sofiya, TANASESCU, Radu, ZUMBÜHL, Andreas
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The invention relates to liposome vesicle comprising a membrane consisting of 1,3-diheptadecanamidopropan-2-yl (2-(trimethylammonio) ethyl) phosphate surrounding a volume comprising a pharmaceutical drug or contrast agent. The vesicle is mechanosensitive at body temperature and at physiologically or pathophysiologically relevant shear stress.