FUSED IMIDAZOLE DERIVATIVES AS IL-17 MODULATORS

FUSED IMIDAZOLE DERIVATIVES AS IL-17 MODULATORS

A series of substituted fused bicyclic imidazole derivatives, including benzimidazole derivatives and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune dis...

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Bibliographische Detailangaben
Hauptverfasser: YAU, Wei Tsung, ZHU, Zhaoning, TAYLOR, Richard David, HORSLEY, Helen Tracey, SCHULZE, Monika-Sarah Elisabeth Dorothea, FOULKES, Gregory, BRACE, Gareth Neil, CHAPPELL, Rose Elizabeth, FROST, James Richard, JONES, Elizabeth Pearl, REUBERSON, James Thomas, LECOMTE, Fabien Claude
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A series of substituted fused bicyclic imidazole derivatives, including benzimidazole derivatives and analogues thereof, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.