SINGLE CELL GEL ELECTROPHORESIS

For the use of a single cell gel electrophoresis device for screening a subject for at least a DNA-damage, in particular a specific DNA-damage, in relation to a predisposition for and/or the presence of a disease a carrier plate and a liquid sample is provided. The liquid sample comprises cells of t...

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Bibliographische Detailangaben
Hauptverfasser:	FAISST, Arne-Christian, SCHICHT, Oliver
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	For the use of a single cell gel electrophoresis device for screening a subject for at least a DNA-damage, in particular a specific DNA-damage, in relation to a predisposition for and/or the presence of a disease a carrier plate and a liquid sample is provided. The liquid sample comprises cells of the subject.A single cell gel electrophoresis on the sample of the subject is performed by:- positioning the sample accommodated on the carrier plate in the generated homogenous electrical field and- controlling strength and direction of the electrical field while the sample is positioned in the gel electrophoresis device.The DNA-damage is determined with a high reproducibility, with a coefficient of variation (CV) of 15 % or less, in particular 10 % or less, in particular 5 % or less.