CYCLIC ORALLY DISINTEGRATING TABLET

Provided is an orally disintegrating tablet which can be combined with a variety of drugs and exhibits excellent disintegrating properties in an oral cavity in spite of having a strength and the like which allows a form as a tablet to be maintained. According to the present invention, provided is th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: OKUDA, Yutaka, HONJO, Tatsuya, SAEKI, Isamu
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:Provided is an orally disintegrating tablet which can be combined with a variety of drugs and exhibits excellent disintegrating properties in an oral cavity in spite of having a strength and the like which allows a form as a tablet to be maintained. According to the present invention, provided is the annular orally disintegrating tablet containing a drug and a disintegrating agent; and having a hole in a central portion thereof and being annular, and a content of the disintegrating agent relative to a total weight thereof is 2% by weight or more and 50% by weight or less, the annular orally disintegrating tablet exhibiting the excellent disintegrating properties, in which when a gradient of a disintegrating time (seconds) of the annular orally disintegrating tablet with respect to a tableting pressure (kN) upon compression forming is defined as a and a gradient of a disintegrating time (seconds) of a disk-shaped orally disintegrating tablet with respect to a tableting pressure (kN) upon compression forming is defined as b, the disk-shaped orally disintegrating tablet having the same weight and external diameter as the weight and external diameter of the annular orally disintegrating tablet and having no hole, a ratio (a/b) between the gradient a and the gradient b is 0.90 or less.