BISPECIFIC ANTIBODY FOR ICOS AND PD-L1

Multispecific antibody in mAb2 format, comprising an ICOS-binding Fab region and a PD-L1-binding Fcab region. Use of the multispecific antibody in immuno-oncology, including for treatment of solid tumours. Combination therapy including antibody to another immune checkpoint molecule such as PD-1 and...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	MCCOURT, Matthew John, TUNA, Mihriban, WOLLERTON VAN HORCK, Francisca, ARKINSTALL, Stephen John, BADR, Fadi, FIEHLER, Ryan, CAMPBELL, Jamie Iain, AKELE, Frederik, SAINSON, Richard Charles Alfred, FAROUDI, Mustapha
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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