FORMULATION OPTIMIZATION FOR VIRAL PARTICLES

The present disclosure provides formulations for maintaining viral particles in a stable form. In certain embodiments, the formulation comprises at least one basic amino acid and a buffer solution, wherein the viral particle is present at a concentration of about 1×1011 to about 5×1013 DNase resista...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GASKIN, Chantelle, KNOP, David, R, LONG, Yuyu
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present disclosure provides formulations for maintaining viral particles in a stable form. In certain embodiments, the formulation comprises at least one basic amino acid and a buffer solution, wherein the viral particle is present at a concentration of about 1×1011 to about 5×1013 DNase resistant virus particles per mL.