PREPARATION FOR MAGNETIC RESONANCE DIAGNOSTICS FOR ONCOLOGICAL DISEASES, COMPRISING DEUTERATED 3-O-METHYLGLUCOSE, AND DIAGNOSTIC METHOD USING SAID PREPARATION

The invention relates to medicine, namely to the means for magnetic resonance imaging of the oncological diseases. For this purpose, the diagnostic agent and the diagnostic method based on the use of the diagnostic agent is developed, which is based on a deuterated derivative of 3-O-methylglucose or...

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Hauptverfasser:	IVASHKIN, Pavel Evgenievich, DOROFEEVA, Evgeniya Olegovna, POLSHAKOV, Vladimir Ivanovich, KOSENKOV, Aleksei Viktorovich, LESIV, Aleksei Valerievich, GULYAEV, Mikhail Vladimirovich, KISELEVSKY, Mikhail Valentinovich
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SUGARS
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Beschreibung
Zusammenfassung:	The invention relates to medicine, namely to the means for magnetic resonance imaging of the oncological diseases. For this purpose, the diagnostic agent and the diagnostic method based on the use of the diagnostic agent is developed, which is based on a deuterated derivative of 3-O-methylglucose or a mixture of at least two different deuterated derivatives of 3-O-methylglucose. The method of the invention involves performing magnetic resonance imaging and/or magnetic resonance spectroscopy at the frequency of deuterium nuclei after administration of the diagnostic medication after a time sufficient for accumulation of the diagnostic medication in the tumor tissue of a subject for receiving, respectively, MR images and/or MR spectra.The proposed method allows diagnosing oncological diseases with high informational content.