FLEXIBLE SYSTEMS, DEVICES AND METHODS FOR EPIDERMAL MONITORING OF ANALYTES AND BIOMARKERS IN FLUIDS ON SKIN

Disclosed are devices, systems and methods for epidermal monitoring of a fluid on skin. In some aspects, a device includes an electrochemical sensor comprising two or more electrodes disposed on a first flexible substrate; a microfluidic device comprising a second flexible substrate coupled to the f...

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Bibliographische Detailangaben
Hauptverfasser: MORETO, Juliane Sempionatto, MORETO, Jose Roberto, GALAN, Aida Martin, CAMPBELL, Alan, KIM, Jayoung, WANG, Joseph, KURNIAWAN, Jonas Felipe
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed are devices, systems and methods for epidermal monitoring of a fluid on skin. In some aspects, a device includes an electrochemical sensor comprising two or more electrodes disposed on a first flexible substrate; a microfluidic device comprising a second flexible substrate coupled to the first substrate and structured to include (i) a channel in a first cavity of the second substrate, (ii) one or more holes that connect to the channel and provide one or more inlets, and (iii) a reservoir connected to the channel, in which the electrochemical sensor is aligned with the reservoir; and an adhesion layer coupled to the microfluidic device and attachable to skin, and the device being operable to detect a biomarker in a fluid in secreted by the skin into the microfluidic device.