BENZIMIDAZOLE DERIVATIVES AND THEIR USES

The present invention relates to inhibitors of Transient Receptor Potential Channel 6 (TRPC6) protein activity. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for man...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HUA, Zihao, SCHENKEL, Laurie, ZHAO, Wei, MILGRAM, Benjamin Charles, WHITE, Ryan D, PANTELEEV, Jane, WEISS, Matthew, CHAKKA, Nagasree, GAO, Hua, GUZMAN-PEREZ, Angel, STELLWAGEN, John, LIN, Daniel C. H, HORNE, Daniel B, KIEFFER, Madeleine, BARTBERGER, Michael D
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to inhibitors of Transient Receptor Potential Channel 6 (TRPC6) protein activity. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.