TABLET CONTAINING VALSARTAN AND SACUBITRIL

The present invention relates to a tablet for oral administration containing valsartan and sacubitril, preferably as sodium salts or as a complex of valsartan disodium and sacubitril monosodium, preferably LCZ696. The tablet is prepared by dry-granulation or direct compression and contains a mesopor...

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Bibliographische Detailangaben
Hauptverfasser: PRATHAP, Vamshi Ramana, RUCHATZ, Dieter, BANDLA, Srimannarayana, SCHLEHAHN, Hendrik, VELUSAMY, Bala Subramanian, RALLABANDI, Bala Ramesha Chary, GOLLAPUDI, Krishna Mohan
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a tablet for oral administration containing valsartan and sacubitril, preferably as sodium salts or as a complex of valsartan disodium and sacubitril monosodium, preferably LCZ696. The tablet is prepared by dry-granulation or direct compression and contains a mesoporous inorganic stabilizer, e.g. mesoporous silica (Syloid®).