BISPECIFIC ANTIBODY

The present invention addresses the problem of providing a novel medical agent for prevention of auto-immune diseases, inhibition of symptom progression thereof, inhibition of recurrence thereof, or treatment thereof. As a result of conducting extensive studies, the inventors of the present inventio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SHIBAYAMA, Shiro, TEZUKA, Tomoya
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention addresses the problem of providing a novel medical agent for prevention of auto-immune diseases, inhibition of symptom progression thereof, inhibition of recurrence thereof, or treatment thereof. As a result of conducting extensive studies, the inventors of the present invention have focused attention on PD-1/CD19 bispecific antibody as a substance with the potentiality of solving the problem, and have achieved the present invention. The PD-1/CD19 bispecific antibody according to the present invention exhibits growth-inhibitory action and immunoglobulin production inhibitory action against activated B cells, and also has inhibitory action against production of cytokine from memory T cells.