CONJUGATED PROTEINS AND USES THEREOF

Disclosed herein, in certain embodiments, are protein-probe adducts and synthetic ligands that inhibit protein-probe adduct formation, in which the proteins are regulated by NRF2. In some instances, also described herein are protein-binding domains that interact with a probe and/or a ligand describe...

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Bibliographische Detailangaben
Hauptverfasser: CRAVATT, Benjamin F, BAR-PELED, Liron, KEMPER, Esther
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Disclosed herein, in certain embodiments, are protein-probe adducts and synthetic ligands that inhibit protein-probe adduct formation, in which the proteins are regulated by NRF2. In some instances, also described herein are protein-binding domains that interact with a probe and/or a ligand described herein, in which the proteins are regulated by NRF2.