MACROCYCLIC IMMUNOMODULATORS

MACROCYCLIC IMMUNOMODULATORS

Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I) or (II):including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R6c, m and n are as defined herein. Methods associated with prep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PUNNA, Sreenivas, SINGH, Rajinder, ZHANG, Penglie, MALATHONG, Viengkham, MCMURTRIE, Darren, J, ROTH, Howard, S, MCMAHON, Jeffrey
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I) or (II):including stereoisomers and pharmaceutically acceptable salts thereof, wherein R, R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R6c, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.