AMORPHOUS AND CRYSTALLINE FORMS OF IDO INHIBITORS

AMORPHOUS AND CRYSTALLINE FORMS OF IDO INHIBITORS

The present disclosure relates to amorphous and crystalline forms of (R)-N-(4-chlorophenyl)-2-(1S,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide and its salts and hydrates, processes for their production, pharmaceutical compositions comprising them, and methods of treatment using them.

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Bibliographische Detailangaben
Hauptverfasser: VLAHOVA, Petinka, BECK, Hilary, Plake, WALKER, James, Ross, YOUNG, Ian, Scott, SHUNATONA, Hunter, Paul, POWERS, Jay, Patrick, NELSON, Jennifer, REILLY, Maureen, Kay, ROSENBAUM, Tamar, OSIPOV, Maksim, ZIBINSKY, Mikhail
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure relates to amorphous and crystalline forms of (R)-N-(4-chlorophenyl)-2-(1S,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide and its salts and hydrates, processes for their production, pharmaceutical compositions comprising them, and methods of treatment using them.