SYSTEMS FOR MAKING BASE CALLS IN NUCLEIC ACID SEQUENCING

A system includes a machine-readable memory and a processor. The processor is configured to execute machine-readable instructions which, when executed by the processor, cause the system to perform the following steps: receiving signals being responsive to nucleotide flows, determining whether a defi...

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Bibliographische Detailangaben
Hauptverfasser: SIKORA, Marcin, KOLLER, Christian, CAWLEY, Simon, DAVEY, Melville, WILLIAMS, Alan, KULP, David
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A system includes a machine-readable memory and a processor. The processor is configured to execute machine-readable instructions which, when executed by the processor, cause the system to perform the following steps: receiving signals being responsive to nucleotide flows, determining whether a defined space comprises one or more sample nucleic acids, processing a signal to improve a quality of the signal, generating a set of candidate sequences of bases for the defined space, and selecting a candidate sequence as corresponding to the correct sequence for the one or more sample nucleic acids in the defined space.