LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS

This invention provides for a compound of formula (I):or a pharmaceutically acceptable salt thereof, wherein R1-R4, L and X are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells...

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Bibliographische Detailangaben
Hauptverfasser:	BYERS, Crystal, ZHAO, Junping, FAZAL, Tanzina, BOWMAN, Keith, GAMBER, Gabriel Grant, ZABAWA, Thomas, WANG, Shuangxi, TICHKULE, Ritesh Bhanudasji, LEE, Cameron Chuck-Munn, VARGEESE, Chandra, BECKWITH, Rohan Eric John, BARYZA, Jeremy Lee, WEST, Laura
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention provides for a compound of formula (I):or a pharmaceutically acceptable salt thereof, wherein R1-R4, L and X are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.