HYDROPHILIC POLYMER DERIVATIVE HAVING SELF-IMMOLATIVE ACETAL LINKER AND COMPOSITE USING SAME

HYDROPHILIC POLYMER DERIVATIVE HAVING SELF-IMMOLATIVE ACETAL LINKER AND COMPOSITE USING SAME

To provide a hydrophilic polymer derivative having a novel linker technique which is able to from a hydrophilic polymer pro-drug of a drug containing an amino group or the like in order to overcome the restrictions of conventional hydrophilic polymer pro-drugs. A hydrophilic polymer derivative conta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TAMAGAWA Shinya, TSUBUSAKI Takuma
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
COMPOSITIONS BASED THEREON
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:To provide a hydrophilic polymer derivative having a novel linker technique which is able to from a hydrophilic polymer pro-drug of a drug containing an amino group or the like in order to overcome the restrictions of conventional hydrophilic polymer pro-drugs. A hydrophilic polymer derivative containing a hydrophilic polymer moiety and an acetal moiety, wherein the hydrophilic polymer derivative contains a structure represented by formula (1) or formula (2):