ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF

The present application relates to compounds of formula Iwherein R1, R2and R3are as defined herein and such compounds are for use in a method of treating, preventing or managing cancer. Said cancer can be leukemia. Said method can further comprise administering a second agent. Pharmaceutical composi...

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Bibliographische Detailangaben
Hauptverfasser:	LOPEZ-GIRONA, Antonia, CORREA, Matthew Daniel, POURDEHNAD, Michael, HANSEN, Joshua, MULLER, George W, CATHERS, Brian Edwin, MACBETH, Kyle J, RAHEJA, Raj Kumar, Man, Hon-Wah, Khalil, Ehab M
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present application relates to compounds of formula Iwherein R1, R2and R3are as defined herein and such compounds are for use in a method of treating, preventing or managing cancer. Said cancer can be leukemia. Said method can further comprise administering a second agent. Pharmaceutical compositions and single unit dosage forms comprising such compounds are also provided.