CD147 ANTIBODIES, ACTIVATABLE CD147 ANTIBODIES, AND METHODS OF MAKING AND USE THEREOF

CD147 ANTIBODIES, ACTIVATABLE CD147 ANTIBODIES, AND METHODS OF MAKING AND USE THEREOF

The invention relates generally to antibodies that bind CD147, activatable antibodies that bind to CD147 and methods of making and using these antibodies and activatable antibodies in a variety of therapeutic, prophylactic, and diagnostic contexts. In some embodiments, the CD147 antibodies and CD147...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: WEST, James William, SAGERT, Jason Gary, TERRETT, Jonathan Alexander, LIN, Shuoyen Jack
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates generally to antibodies that bind CD147, activatable antibodies that bind to CD147 and methods of making and using these antibodies and activatable antibodies in a variety of therapeutic, prophylactic, and diagnostic contexts. In some embodiments, the CD147 antibodies and CD147 activatable antibodies bind human and cynomolgus monkey CD147.