PROCESSES FOR THE PREPARATION OF FUNGICIDAL COMPOUNDS

Provided herein are processes for the preparation of stereomerically enriched compounds of Formulas I-014, I-020, I-064, I-074, I-082, I-089, I-090, I-095, I-171, I-181, I-184, I-186, I-189, I-191, I-192, I-193, I-205, I-206, I-208, I-211, I-212, I-213, I-220, I-229, I-231, I-233, I-234, I-246, I-25...

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Hauptverfasser: HARRIMAN, Geraldine C, LEIGHTY, Matthew W, LEIT DE MORADEI, Silvana Marcel, MILLER, William H, GHOSH, Shomir, WALKER, Daniel P, LAWSON, Jon P, SCHOSTAREZ, Heinrich J, SLOMCZYNSKA, Urszula J, POEL, Toni-Jo, SIMONS, Lloyd J
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided herein are processes for the preparation of stereomerically enriched compounds of Formulas I-014, I-020, I-064, I-074, I-082, I-089, I-090, I-095, I-171, I-181, I-184, I-186, I-189, I-191, I-192, I-193, I-205, I-206, I-208, I-211, I-212, I-213, I-220, I-229, I-231, I-233, I-234, I-246, I-251, I-258, I-259, I-262, I-263, I-285, I-323 and I-400. The compounds described herein exhibit activity as pesticides and are useful, for example, in methods for the control of fungal pathogens and diseases caused by fungal pathogens in plants. A preferred process is directed to preparing a stereomerically enriched compound of Formula V-1 or V-2-F by assymetrical reduction in the presence of a chiral organometallic catalyst.