AUTOASSOCIATIVE ACRYLIC FUNCTIONAL COPOLYMERS AND TERPOLYMERS AND THEIR USE AS VEHICLES OF BIOACTIVE COMPOUNDS

The present invention relates to a family of amphiphilic copolymers and terpolymers forming nanometric-sized bioactive polymeric multi-micellar nanoparticles, consisting of synthetic polymer systems derived from acrylic functional monomers containing α-tocopherol (vitamin E) as a bioactive and hydro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	SAN ROMÁN DEL BARRIO, Julio, PALAO SUAY, Raquel, AGUILAR DE ARMAS, María Rosa, NAKAL, Alberto
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G CHEMISTRY COMPOSITIONS BASED THEREON GENERAL PROCESSES OF COMPOUNDING HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP WORKING-UP
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to a family of amphiphilic copolymers and terpolymers forming nanometric-sized bioactive polymeric multi-micellar nanoparticles, consisting of synthetic polymer systems derived from acrylic functional monomers containing α-tocopherol (vitamin E) as a bioactive and hydrophobic component, and hydrophilic monomers with a highly variable composition, preferably consisting of N-vinylpyrrolidone, N-vinyl caprolactam, N-vinyl imidazole, as well as mixtures of vitamin E methacrylate and N-vinyl pyrrolidone copolymers with the corresponding terpolymers. These compounds can be used as controlled release systems for the administration of bioactive compounds.