METHOD FOR THE SYNTHESIS OF DNA CONJUGATES BY MICELLAR CATALYSIS

The present invention relates to a compound library comprising a plurality of conjugate molecules, wherein said conjugates comprise a small organic molecule covalently coupled to a nucleic acid moiety, wherein the nucleic acid moiety consists of pyrimidine nucleotides and the plurality of conjugates...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	BRUNSCHWEIGER, Andreas, KLIKA SKOPIC, Mateja, WEBERSKIRCH, Ralf, BHAT, Avinash Shashidhar
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC MACROMOLECULAR COMPOUNDS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS THEIR PREPARATION OR CHEMICAL WORKING-UP VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a compound library comprising a plurality of conjugate molecules, wherein said conjugates comprise a small organic molecule covalently coupled to a nucleic acid moiety, wherein the nucleic acid moiety consists of pyrimidine nucleotides and the plurality of conjugates differ from each other at least by comprising different organic molecules. Further, the present invention relates to the use of said library for screening compounds binding to a target molecule and methods of synthesizing said library.