CXCR2 BINDING POLYPEPTIDES

The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the pol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Steffensen, Soren, Brown, Zarin, Dombrecht, Bruno, Bradley, Michelle, Charlton, Steven, John, Cromie, Karen, Van Heeke, Gino
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2.