SYSTEMS, METHODS, AND DEVICES FOR STOPPING OR REDUCING LEAKS IN A CHROMATOGRAPHY SYSTEM

Systems, methods, and devices for detecting leaks in chromatography systems are disclosed. A coating is disposed to conform to at least one component of a chromatography system, such as a fitting or a section of tubing. The coating is made of or contains a responsive material that can undergo a dete...

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Bibliographische Detailangaben
Hauptverfasser: JUNG, Moon Chul, TARAFDER, Abhijit, SONG, Xiangjin, BROUSMICHE, Darryl W, BELANGER, Jonathan L, LEVEILLE, Wade P
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Systems, methods, and devices for detecting leaks in chromatography systems are disclosed. A coating is disposed to conform to at least one component of a chromatography system, such as a fitting or a section of tubing. The coating is made of or contains a responsive material that can undergo a detectable change when exposed to a chromatographic fluid or mobile phase. The change of the responsive material can indicate the presence of the fluid or mobile phase, a change in at least one physical property of the coating to prevent passage of the fluid or mobile phase, or a combination thereof.