CHIMERIC ANTIGEN RECEPTOR AND NATURAL KILLER CELLS EXPRESSING SAME

The present invention relates to a chimeric antigen receptor and natural killer cells expressing the same and, more particularly, to a chimeric antigen receptor (CAR) comprising an intracellular signaling domain including all or a part of an OX40 ligand (CD252), thereby having an excellent anticance...

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Bibliographische Detailangaben
Hauptverfasser: JUNG, Mi Young, LEE, Eun Sol, HER, Jung Hyun, WON, Sung Yong, KIM, Han Sol, KIM, Hyun Ah, LIM, Ho Yong, HWANG, Yu Kyeong, CHO, Sung Yoo, GWON, Su Hyun
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a chimeric antigen receptor and natural killer cells expressing the same and, more particularly, to a chimeric antigen receptor (CAR) comprising an intracellular signaling domain including all or a part of an OX40 ligand (CD252), thereby having an excellent anticancer activity enhancing effect on immune cells, and immune cells expressing the same.