METHODS AND COMPOSITIONS RELATED TO THIOESTERASE ENZYMES

The present invention relates to novel mutant thioesterase enzymes and naturally-occurring equivalents thereof, compositions made from such enzymes and uses of thioesterase enzymes. In particular, the present invention provides mutant thioesterase enzymes that have altered properties, for example, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HOM, Louis, TRINH, Na, ALIBHAI, Murtaza
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	ADDING MATERIALS TO FUELS OR FIRES TO REDUCE SMOKE ORUNDESIRABLE DEPOSITS OR TO FACILITATE SOOT REMOVAL BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FIRELIGHTERS FUELS FUELS NOT OTHERWISE PROVIDED FOR LIQUEFIED PETROLEUM GAS LUBRICANTS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NATURAL GAS PEAT PETROLEUM, GAS OR COKE INDUSTRIES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SYNTHETIC NATURAL GAS OBTAINED BY PROCESSES NOT COVERED BYSUBCLASSES C10G, C10K TECHNICAL GASES CONTAINING CARBON MONOXIDE VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to novel mutant thioesterase enzymes and naturally-occurring equivalents thereof, compositions made from such enzymes and uses of thioesterase enzymes. In particular, the present invention provides mutant thioesterase enzymes that have altered properties, for example, altered substrate specificity, altered activity, altered selectivity, and/or altered proportional yields in the product mixtures. The present invention also provides polynucleotides encoding such mutant thioesterase enzymes, and vectors and host cells comprising such polynucleotides. The invention further provides for novel uses of thioesterases in the production of various fatty acid derivatives, which are useful as, or as components of, industrial chemicals and fuels.