ETHER LINKED TRIAZOLES AS NRF2 REGULATORS

The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof:

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Hauptverfasser: HEIGHTMAN, Thomas Daniel, KERNS, Jeffrey K, COOPER, Anthony William James, GOODWIN, Nicole Cathleen, GRIFFITHS-JONES, Charlotte Mary, YAN, Hongxing, WILLEMS, Hendrika Maria Gerarda
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creator HEIGHTMAN, Thomas Daniel
KERNS, Jeffrey K
COOPER, Anthony William James
GOODWIN, Nicole Cathleen
GRIFFITHS-JONES, Charlotte Mary
YAN, Hongxing
WILLEMS, Hendrika Maria Gerarda
description The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof:
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ETHER LINKED TRIAZOLES AS NRF2 REGULATORS
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