ETHER LINKED TRIAZOLES AS NRF2 REGULATORS

The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof:

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Bibliographische Detailangaben
Hauptverfasser: HEIGHTMAN, Thomas Daniel, KERNS, Jeffrey K, COOPER, Anthony William James, GOODWIN, Nicole Cathleen, GRIFFITHS-JONES, Charlotte Mary, YAN, Hongxing, WILLEMS, Hendrika Maria Gerarda
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to ether-linked triazole compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof: