EXOSOMES FOR DELIVERY OF THERAPEUTIC AGENTS

The present invention provides exosomes as drug delivery vehicles, compositions comprising a therapeutic agent encapsulated within such exosomes, methods of producing such exosomes and compositions thereof, as well as methods of delivering such exosomes and compositions to a specific patient tissue...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHYAM, Rishab R, BONNER, Daniel Kenneth, MUTAMBA, James Tendai, JANTZ, John, FERREIRA, Lisa V, BOLEN, Joseph, KRUMOVA, Katerina
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention provides exosomes as drug delivery vehicles, compositions comprising a therapeutic agent encapsulated within such exosomes, methods of producing such exosomes and compositions thereof, as well as methods of delivering such exosomes and compositions to a specific patient tissue or organ. The present invention also provides methods of treating a disease, disorder, or condition such as cancer, an inflammatory disease, an infectious disease, an allergic disease, or an autoimmune disease, comprising administering to a patient in need thereof a provided therapeutic-loaded exosome or a pharmaceutical composition thereof.