TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR

Compounds of Formula (I) and Formula (II), pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula (I) and Formula (II) have the following...

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Bibliographische Detailangaben
Hauptverfasser:	DRANSFIELD, Paul John, YEH, Wen-Chen, MIHALIC, Jeffrey T, HARVEY, James S, HEUMANN, Lars V, KAYSER, Frank, CONNORS, Richard V, HEATH, Julie Anne, DEIGNAN, Jeffrey, CHEN, Yinhong, KHAKOO, Aarif Yusuf, CHENG, Alan C, WANG, Xiaodong, FU, Zice, SWAMINATH, Gayathri, HOUZE, Jonathan, MA, Zhihua, BROWN, Matthew, LAI, Su-Jen, KOPECKY, David J, OLSON, Steven H, PATTAROPONG, Vatee, CHEN, Xiaoqi, WANSKA, Malgorzata, MEDINA, Julio C, DU, Xiaohui, CHEN, Ning
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of Formula (I) and Formula (II), pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula (I) and Formula (II) have the following structures: (I); (II). Intermediates (V) are also claimed.