METHOD FOR THE IMMUNOLOGICAL DIAGNOSIS OF A SAMPLE WITH A POTENTIAL INFECTION WITH AN ARBOVIRUS AND TEST KITS SUITABLE FOR THIS PURPOSE

The present invention relates to a method for the immunological diagnosis of a sample from a patient with a potential infection with an arbovirus, wherein a) a sample is brought into contact with a plurality of antigens provided such that they are separated from one another on a solid phase, at leas...

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Bibliographische Detailangaben
Hauptverfasser: SOUTSCHEK, Erwin, BÖCHER, Oliver, NÖLTING, Christina
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention relates to a method for the immunological diagnosis of a sample from a patient with a potential infection with an arbovirus, wherein a) a sample is brought into contact with a plurality of antigens provided such that they are separated from one another on a solid phase, at least the following antigens being used: aa) the "non-structural protein 1" of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, bb) an "envelope protein" of a first arbovirus or an immunologically reactive part thereof having at least 8 amino acids, cc) an "envelope protein" of a second arbovirus or an immunologically reactive part thereof having at least 8 amino acids, dd) the "non-structural protein 1" of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids and ee) an "envelope protein" of a third arbovirus or an immunologically reactive part thereof having at least 8 amino acids, b) the solid phase is washed to separate non-specific bindings, c) the immune complex formed on the solid phase is converted into a signal and d) the test method is evaluated by comparing the relative signal strengths.