NAPHTHYRIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ARRHYTHMIA

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof:wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of phar...

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Hauptverfasser: GULGEZE EFTHYMIOU, Hatice Belgin, SMITH, Nichola, BARBE, Guillaume, GENG, Sicong, YAMADA, Ken, BEBERNITZ, Gregory Raymond, MA, Fupeng, YASOSHIMA, Kayo, PARKER, David Thomas, PENG, Yunshan, LIAO, Lv, MO, Ruowei, PEUKERT, Stefan
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creator GULGEZE EFTHYMIOU, Hatice Belgin
SMITH, Nichola
BARBE, Guillaume
GENG, Sicong
YAMADA, Ken
BEBERNITZ, Gregory Raymond
MA, Fupeng
YASOSHIMA, Kayo
PARKER, David Thomas
PENG, Yunshan
LIAO, Lv
MO, Ruowei
PEUKERT, Stefan
description The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof:wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NAPHTHYRIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ARRHYTHMIA
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