NAPHTHYRIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ARRHYTHMIA

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof:wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of phar...

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Bibliographische Detailangaben
Hauptverfasser:	GULGEZE EFTHYMIOU, Hatice Belgin, SMITH, Nichola, BARBE, Guillaume, GENG, Sicong, YAMADA, Ken, BEBERNITZ, Gregory Raymond, MA, Fupeng, YASOSHIMA, Kayo, PARKER, David Thomas, PENG, Yunshan, LIAO, Lv, MO, Ruowei, PEUKERT, Stefan
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof:wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.