FIBRIN COMPOSITION COMPRISING CARRIER MATERIAL, METHOD AND WOUND ARTICLES

Provided is a method of forming a fibrin hydrogel composition, the method including providing a fibrin hydrogel or precursor thereof, comprising fibrin hydrogel forming salt. The fibrin hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrin hydro...

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Bibliographische Detailangaben
Hauptverfasser: O'HARE, Jonathan J, TIAN, Zhicheng, BJORK, Jason W, DIZIO, James P, ASMUS, Robert A, DETERMAN, Amy S
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided is a method of forming a fibrin hydrogel composition, the method including providing a fibrin hydrogel or precursor thereof, comprising fibrin hydrogel forming salt. The fibrin hydrogel forming salt concentration is greater than or equal to the threshold concentration to form a fibrin hydrogel. The method further includes combining the fibrin hydrogel with a carrier material. The concentration of the carrier material typically ranges from 0.1 to about 50 wt.-%. The method further includes reducing the salt concentration below the threshold concentration to form a fibrin hydrogel.