MNK INHIBITORS AND METHODS RELATED THERETO

The present invention relates to compounds according to Formula (I):or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, R, R, R, W, W, Y andare as defined herein. Also described are pharmaceutically acceptable compositions of Formula I compounds as well...

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Hauptverfasser: SPRENGELER, Paul A, WEBBER, Stephen E, REICH, Siegfried H, XIANG, Alan Xin, ERNST, Justin Thomas
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creator SPRENGELER, Paul A
WEBBER, Stephen E
REICH, Siegfried H
XIANG, Alan Xin
ERNST, Justin Thomas
description The present invention relates to compounds according to Formula (I):or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, R, R, R, W, W, Y andare as defined herein. Also described are pharmaceutically acceptable compositions of Formula I compounds as well as methods for utilizing the compounds of Formula I and the pharmaceutically acceptable compositions of Formula I compounds as inhibitors of Mnk as well as therapeutics for the treatment of diseases such as cancer.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title MNK INHIBITORS AND METHODS RELATED THERETO
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