MNK INHIBITORS AND METHODS RELATED THERETO

The present invention relates to compounds according to Formula (I):or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, R, R, R, W, W, Y andare as defined herein. Also described are pharmaceutically acceptable compositions of Formula I compounds as well...

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Bibliographische Detailangaben
Hauptverfasser:	SPRENGELER, Paul A, WEBBER, Stephen E, REICH, Siegfried H, XIANG, Alan Xin, ERNST, Justin Thomas
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to compounds according to Formula (I):or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, R, R, R, W, W, Y andare as defined herein. Also described are pharmaceutically acceptable compositions of Formula I compounds as well as methods for utilizing the compounds of Formula I and the pharmaceutically acceptable compositions of Formula I compounds as inhibitors of Mnk as well as therapeutics for the treatment of diseases such as cancer.