COMPOSITION FOR HEPATIC ARTERIAL CHEMOEMBOLIZATION USING HUMAN SERUM ALBUMIN NANOPARTICLES CARRYING ANTICANCER AGENT, AND METHOD FOR PRODUCING SAME

COMPOSITION FOR HEPATIC ARTERIAL CHEMOEMBOLIZATION USING HUMAN SERUM ALBUMIN NANOPARTICLES CARRYING ANTICANCER AGENT, AND METHOD FOR PRODUCING SAME

The present invention aims to dramatically increase the effect of hepatic arterial chemoembolization by developing human serum albumin-based nanoparticles, which are bioproteins that effectively carry Adriamycin in place of Adriamycin, an anticancer agent used in hepatic arterial chemoembolization....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHUNG, Jin Wook, KIM, Hyun Cheol, JUNG, Eun Ah
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention aims to dramatically increase the effect of hepatic arterial chemoembolization by developing human serum albumin-based nanoparticles, which are bioproteins that effectively carry Adriamycin in place of Adriamycin, an anticancer agent used in hepatic arterial chemoembolization. The human serum albumin nanoparticles carrying the Adriamycin not only intensively infiltrate the drug effectively into the cells but also have a synergistic effect that can induce a long-term therapeutic effect by utilizing the effect of continuous drug release from the particles.