IMMUNOGENIC WT1 PEPTIDES AND USE THEREOF

IMMUNOGENIC WT1 PEPTIDES AND USE THEREOF

WTl-specific cytotoxic T lymphocytes (CTL), CD8+lymphocytes or CD4+lymphocytes, obtained by a method comprising contacting a lymphocyte cell populationin vitroorex vivowith one or more specific WT1 peptides, thereby inducing the formation and proliferation of the WT1-specific lymphocytes, for use in...

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Bibliographische Detailangaben
Hauptverfasser: SELVAKUMAR, Annamalai, O REILLY, Richard J, DOUBROVINA, Ekaterina
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:WTl-specific cytotoxic T lymphocytes (CTL), CD8+lymphocytes or CD4+lymphocytes, obtained by a method comprising contacting a lymphocyte cell populationin vitroorex vivowith one or more specific WT1 peptides, thereby inducing the formation and proliferation of the WT1-specific lymphocytes, for use in treating a subject with a WT1-expressing cancer or for use in reducing the incidence of a WT1-expressing cancer or its relapse.