TRPV4 ANTAGONISTS

The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.

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Bibliographische Detailangaben
Hauptverfasser:	BRNARDIC, Edward J, TERRELL, Lamont Roscoe, BEHM, David J, THOMAS, James V, MCATEE, John Jeffrey, BROOKS, Carl A, LAWHORN, Brian Griffin, BARTON, Linda S, PERO, Joseph E, PATTERSON, Jaclyn R, SENDER, Matthew Robert, SANCHEZ, Robert, BUDZIK, Brian W, MATTHEWS, Jay M, YE, Guosen
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to pyrrolidine sulfonamide analogs, pharmaceutical compositions containing them and their use as TRPV4 antagonists.