MAGNETIC PARTICLE-BINDING PEPTIDES

MAGNETIC PARTICLE-BINDING PEPTIDES

The present invention relates to a peptide consisting of a sequence of 5 to 30, preferably 6 to 12, most preferably 10 to 12 amino acids, wherein (a) at least ⅔ of said amino acids have a functional group or side chain which is negatively charged at neutral pH; (b) amino acids which do not have a fu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BORKOWSKA-PANEK, Monika, BLANK-SHIM, Silvia, FINK, Karin, SCHWAMINGER, Sebastian, WENZEL, Wolfgang, FRAGA GARCIA, Paula, BERENSMEIER, Sonja, ANAND, Priya
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention relates to a peptide consisting of a sequence of 5 to 30, preferably 6 to 12, most preferably 10 to 12 amino acids, wherein (a) at least ⅔ of said amino acids have a functional group or side chain which is negatively charged at neutral pH; (b) amino acids which do not have a functional group or side chain which is negatively charged at neutral pH, if present, meet one or both of requirements (i) and (ii): (i) none of them has a functional group or side chain which is positively charged at neutral pH; and (ii) at least one of them has a side chain which does not bear a net charge at neutral pH or which has a functional group or side chain that does not bear a net charge at neutral pH.