BIOSYNTHETIC HEPARIN

The present disclosure relates to synthesis of heparin, which may be bioequivalent to porcine USP Heparin Sodium. The synthesis may involve three intermediates starting from heparosan.

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Bibliographische Detailangaben
Hauptverfasser: DORDICK, Jonathan, BRODFUEHRER, Paul, MORI, Daisuke, FU, Li, DATTA, Payel, LIN, Lei, GROVER, Navdeep, PASKALEVA, Elena, DOUAISI, Marc, LI, Kevin, HIRAKANE, Makoto, ONISHI, Akihiro, SIMMONS, Trevor J, LINHARDT, Robert J
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present disclosure relates to synthesis of heparin, which may be bioequivalent to porcine USP Heparin Sodium. The synthesis may involve three intermediates starting from heparosan.