ANALYSIS SYSTEMS

We describe instruments, and cartridges therefor, for processing droplets of water in oil-in-water emulsions, the droplets containing biological entities such as cells. A microfluidic cartridge for automated sorting and dispensing of sorted microfluidic droplets comprises a sorting input channel cou...

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Bibliographische Detailangaben
Hauptverfasser:	Pawate, Vinayaka C, Day, Richard Francis, Rehak, Marian, Liu, Xin, Smith, Clive A, Hazell, Michael Stuart, Li, Xin, Marchington, Robert Frank, Craig, Frank F, Benazzi, Giuseppe, Holmes, David
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS TESTING TRANSPORTING
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Beschreibung
Zusammenfassung:	We describe instruments, and cartridges therefor, for processing droplets of water in oil-in-water emulsions, the droplets containing biological entities such as cells. A microfluidic cartridge for automated sorting and dispensing of sorted microfluidic droplets comprises a sorting input channel coupled to a sorting region, the sorting region comprising two or more sorting output channels coupled to the input channel and a droplet director to selectively direct a droplet from the sorting input channel to a selected one of the sorting output channels; and a droplet dispenser coupled to one of the sorting output channels to dispense selected droplets from the cartridge for collection in a reservoir, wherein the droplet dispenser comprises a droplet ejection mechanism to eject droplets from an emulsion flow into a dispenser output channel for collection in the reservoir.