ALL-TRANS RETINOIC ACID INJECTABLE FORMULATION

The present disclosure provides an allretinoic acid injectable formulation and its application for a preparation of a pharmaceutical product for treating tumor. The allretinoic acid injectable formulation includes allretinoic acid and solubilizers. The apparent solubility of the allretinoic acid is...

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Bibliographische Detailangaben
Hauptverfasser:	ZHENG, Anjie, WU, Lieyi, XU, Yuhong, CHEN, Xiaolong
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides an allretinoic acid injectable formulation and its application for a preparation of a pharmaceutical product for treating tumor. The allretinoic acid injectable formulation includes allretinoic acid and solubilizers. The apparent solubility of the allretinoic acid is increased from 0.01 mg/mL to 0.1 mg/mL or more. The injectable formulation can reduce the activity of an infiltrated immuno-suppressive cell population within blood or tumor tissue of a cancer patient, and improve immune clearing effects against tumors. It can be applied independently or together with other pharmaceutical products to inhibit tumor growth and prevent tumor recurrence.