NEW PROCESSES AND INTERMEDIATES FOR NEP INHIBITOR SYNTHESIS

NEW PROCESSES AND INTERMEDIATES FOR NEP INHIBITOR SYNTHESIS

The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril, inter alia via nitro 5 compounds. It further relates to new intermediate compounds and their use for said new chemical synthesis route, as w...

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Bibliographische Detailangaben
Hauptverfasser: SEDELMEIER, Joerg, KLEINBECK-RINIKER, Florian Karl, SEDELMEIER, Gottfried, MARTIN, Benjamin, VENTURONI, Francesco, MAFLI, Ives, PENN, Gerhard
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril, inter alia via nitro 5 compounds. It further relates to new intermediate compounds and their use for said new chemical synthesis route, as well as a new catalyst ligand.